Chromatography

The first high resolution LCMS-ion trap-time-of-flight mass spectrometer

Featuring MSⁿ Capability
Shimadzu's new LCMS-IT-TOF is a novel hybrid mass spectrometer for biomarker discovery, metabolite identification and human health research, and ideal for applications in forensics, drug development, and environmental chemistry. Coupling atmospheric pressure ionization with Ion-Trap (IT) and Time-of-Flight (TOF) technologies, the LCMS-IT-TOF delivers high mass accuracy and high mass resolution (10,000 at 1000 m/z) independent of MS mode.

The LCMS-IT-TOF allows more qualitative information about a sample to be collected in a single run.
This enables researchers and scientists to:

• Elucidate structures of new molecules
• Identify impurities and contaminants
• Analyze metabolites and biomarkers to evaluate biological pathways

The LCMS-IT-TOF has been designed to maximize sensitivity and selectivity by optimizing the ion transport to the TOF analyzer and redefining the capability of the quadrupole ion trap. The ion trap is used to focus ions before ejection into the TOF as well as supporting MSⁿ analysis with effective precursor ion selection capabilities (resolution > 1,000 at 1,000 m/z).